Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

沙利度胺-O-酰胺基-PEG4-C2-NH2 盐酸盐是一种合成的 E3 连接酶配体-连接子缀合物，包含基于沙利度胺的 cereblon 配体和连接子。

Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker.(In Vitro):PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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Others

Other Targets

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2245697-85-0

587.02

C25H35ClN4O10

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (85.18 mM)

Cl.NCCOCCOCCOCCOCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

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(-20℃)

With Ice Pack

≥ 2 years